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Dr Marina Resmini



Prof. Marina Resmini
Professor of Materials Chemistry
School of Biological and Chemical Sciences
Queen Mary, University of London
Mile End Road, E1 4NS London , UK
Tel. +44 (0)207 882 3268
E-mail: m.resmini@qmul.ac.uk

Academic qualifications
1990 Laurea (full marks), Chemistry, University of Milan
1994 PhD, Chemistry, University of Milan , Prof. G. Jommi, “Catalytic antibodies: their production and use as new biocatalysts in organic synthesis”
2000 Post Graduate Certificate in Academic Practice, Queen Mary, University of London

Academic Career
2013 Professor of Materials Chemistry, School of Biological and Chemical Sciences, Queen Mary, University of London
2010 Reader in Organic Chemistry, School of Biological and Chemical Sciences, Queen Mary, University of London
2007-2010 Senior Lecturer in Organic Chemistry, School of Biological and Chemical Sciences, Queen Mary, University of London
1999-2007 Lecturer in Organic Chemistry, School of Biological and Chemical Sciences, Queen Mary, University of London
  September 2003-August 2005 “The Leverhulme Trust” Research Fellow
04/98-12/98 EC Marie Curie Personal Fellowship, Queen Mary, University of London
Awarded for 24 months but terminated on appointment as Lecturer in Organic Chemistry, Queen Mary, University of London
03/96-03/98 Personal Fellowship (Italian Ministry of Research)
University of Milan and Queen Mary, University of London
03/95-02/96 Postdoctoral Fellowship (EC funded) within the European Network on Antibody Catalysis, Queen Mary, University of London, Prof. K. Brocklehurst.
03/94-02/95 Postdoctoral Fellowship (EC funded) within the European Network on Antibody Catalysis, Dept of Chemistry, University of Amsterdam, Prof. U. K. Pandit

biography  

Prof Resmini has a strong research interest on the development of novel functional nanomaterials with potential applications at the physical and life sciences interface; in particular the focus is on the  use of chemical tools to confer special properties to materials for applications as drug delivery systems, catalysts and sensors. She has been active in the field of enzyme mimics and catalytic mechanisms since 1995. Her initial work, as a Marie Curie researcher, focused on the development of monoclonal and polyclonal catalytic antibodies, for a variety of chemical reactions, including the first example of antibody-catalysed hetero Diels-Alder reaction. Mechanistic studies were carried out with hydrolytic polyclonal antibodies to identify the key role played by aminoacid residues in the active site. Collaborative work with Prof. K. Brocklehurst on the mechanistic studies of the papain family of cystein proteinases, using a combination of specially designed time-dependent inhibitors, analogous synthetic substrates and site-directed mutagenesis, was carried out following the award of a Marie Curie personal Fellowship in 1998 and has continued over the years. Following the appointment as a University Lecturer at Queen Mary University of London, the research interests of Prof. Resmini have expanded to investigate novel biomimetic systems using the molecular imprinting approach for the generation of catalytic polymers.

The work has centered on the application of the imprinting technology to flexible polymeric matrices resulting, in 2004, in the first example of molecular imprinted microgels with hydrolytic catalytic activity. In 2008 she consolidated her international standing as one of the world leaders in catalytic imprinted polymers with the recent results on the first imprinted nanogels with Aldolase type I activity, followed by novel nanogels catalyzing the Kemp elimination. She is currently interested in using her acquired expertise on nanomaterials to develop novel drug delivery vehicles and to apply them to pharmaceutically important problems. Her work has been funded by the EPSRC, the Leverhulme Trust, the Royal Society and the European Community while successful industrial collaborations with GlaxoSmithKline, PolyIntell (France) and Sanofi-Aventis (France) are also established.

In June 2010 she was awarded one of the prestigious EPSRC funded award ‘Bright Ideas: Chemistry the big pitch’ to pursue a high risk project on the development of self-disassembling nanogels to be used for drug delivery.

Prof. Resmini has also extensive experience as Project Coordinator of European Commission Marie Skłodowska-Curie Actions (MSCA) chemistry research projects. She was the Coordinator of two successful research projects: NASCENT (FP6 RTN 2006-2010) and IRMED (FP7 IAPP 2010-2014). She is currently the Project Coordinator of two chemistry projects: NANODRUG (FP7 ITN 2011) and IPCOS (HORIZON 2020 ITN 2015).

 

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Queen Mary, University of London, School of Biological and Chemical Sciences, Mile End Road, London E1 4NS, Tel: +44 (0) 20 7882 3268
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