Marina Resmini Research Group
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Marina Resmini Research Group
PUBLICATIONS

PATENTS


56 A.L. Gutiérrez Ortiz, F. Berti, L. Navarini, A. Monteiro, M. Resmini, C. Forzato. Synthesis of p-coumaroylquinic acids and analysis of their interconversion. Tetrahedron: Asymmetry, Volume:28, Issue:3, Pages 419–427, 2017
55. J.V.Ray, F.Mirata, C.Perollier,M.Anrotcarena, S.Bayoudh, M.Resmini, Smart coumarin-tagged imprinted polymers for the rapid detection of tamoxifen. Analytical and bioanalytical Chemistry. Volume:408 Issue:7 Pages: 1855-1861. 2016
54. M.Panagiotopoulou, Y.Salinas, S.Beyazit, S.Kunath, L.Duma, E.Prost, A.G.Mayes, M.Resmini, B.Tse Sum Bui, K.Haupt. Molecularly Imprinted Polymer Coated Quantum Dots for Multiplexed Cell Targeting and Imaging. Angewandte Chemie International edition. Volume: 55 Issue:29 Pages: 8244-8248. 2016
53. M.Resmini, The Leaky Pipeline Chemistry - A European Journal Volume: 22 Issue:11 Special Issue:SI Pages: 3533-3534. 2016
52. K.Zielinska, H.Sun, R.A.Campbell, A.Zarbakhsh, M. Resmini. Smart nanogels at the air/water interface: structural studies by neutron reflectivity. Nanoscale Volume: 8 Issue:9 Pages: 4951-4960. 2016
51. A.R. Jorge, M.Chernobryva, S.E. J. Rigby, M. Watkinson, M. Resmini. Incorporation of Cobalt-Cyclen Complexes into Templated Nanogels Results in Enhanced Activity. Chem Eur J Volume: 22 Issue: 11 Special issue: SI Pages: 3764-3774. 2016. DOI: 10.1002/chem.201503946
50. R. Aksakal, M. Resmini, C.R. Becer. Pentablock star shaped polymers in less than 90 minutes via aqueous SET-LRP. Polymer Chemistry, Volume: 7 Issue:1 Pages: 171-175 2016. DOI: 10.1039/C5PY01623A
49.

S.A.Papadimitriou, Y. Salinas, M. Resmini, Smart Polymeric Nanoparticles as Emerging Tools for Imaging – The Parallel Evolution of Materials. Chemistry - A European Journal Volume: 22 Issue:11 Special Issue:SI Pages: 3612-3620. 2016 DOI: 10.1002/chem.201502610

48. F.Mirata, M. Resmini, Molecular imprinted polymers for catalysis and synthesis. Advances in Biochemic Eng/Biotech, 2015. DOI 10.1007/10_2015_319
47. M. Resmini, Marie Sklodowska-Curie ‘Innovative Training Networks’, Doctoral Education Bulletin, EUA-CDE 2014, 3, 4-5.
46. X.A. Ton, B. Tse Sum Bui, M. Resmini, P. Bonomi, I. Dika, O. Soppera, K. Haupt. A versatile fluorescence fiber optic sensor based on in-situ polymerized molecularly imprinted microstructures. Angewandte Chemie, 2013, 125, 1-6. DOI: 10.1002/ange.201301045
45. Cakir P, Cutivet A, Resmini M, Tse Sum Bui B, Haupt K, Protein-Size Molecularly Imprinted Polymer Nanogels as Synthetic Antibodies, by Localized Polymerization with Multi-initiators Advanced Materials, 2012, Vol. 25, issue 7, pp. 1048-1051, doi: 10.1002/adma.201203400
44. Bonomi, P., Servant, A., Resmini, M., Modulation of imprinting efficiency in nanogels with catalytic activity in the Kemp elimination. Journal of Molecular Recognition, 2012, Vol.25, Issue: 6 Special Issue: SI Pages: 352-360 DOI: 10.1002/jmr.2180
43. Resmini M. Molecularly imprinted polymers as biomimetic catalysts. Analytical and Bioanalytical Chemistry, 2012, Vol. 402, Issue 10, pp. 3021-3026, DOI: 10.1007/s00216-011-5671
42. Resmini M, Flavin K., Carboni D. ‘Microgels and Nanogels with Catalytic activity’ in Molecular Imprinting book series, Topics in Current Chemistry, 2012, Vol. 325, Springer, New York, ISBN 978-3-642-28420-5
41. Servant A, Haupt K, Resmini M. Tuning molecular recognition in water-soluble nanogels with enzyme-like activity for the Kemp elimination. Chem. Eur. J, 2011, Vol.17, Issue 39, pp: 11052-11059. DOI: 10.1002/chem.201002747
40. Hussain S., Khan, A., Gul, S., Resmini, M., Verma, CS, Thomas, EW Brocklehurst, K. Identification of Interactions Involved in the Generation of Nucleophilic Reactivity and of Catalytic Competence in the Catalytic Site Cys/His Ion Pair of Papain. Biochemistry. 2011, 13;50(49):10732-42. doi: 10.1021/bi201207z
39. Pasetto, P., Flavin, K., Resmini, M., “Simple spectroscopic method for the titration of binding sites in molecularly imprinted nanogels with hydrolyase activity” Biosens. Bioelectr. 2009, (33), 25, 572-578.
38. Flavin, K., Resmini, M. “Molecular imprinting with nanomaterials”, chapter in ‘Advanced Nanomaterials’, Eds Geckeler and Nishide, WILEY-VCH, 2009, (2), 651-673.
37. Flavin, K. Resmini, M. “Imprinted nanomaterials: a new class of synthetic receptors” Analytical and Bioanal. Chem. (2009), 393 (2), 437-445. Invited TRENDS article
36. Jorge, A., Watkison M, Resmini M., Biffis A., Svoboda J, ‘Molecular imprinted nanogels as phosphate hydrolysis promoter’,  Abstracts of papers of the American Chemical society, 2009, 238, 63-CATL.
35. Servant A, Haupt K, Resmini, M., ‘Catalytic imprinted nanogels for Kemp elimination: synthesis and characterisation’, Abstracts of papers of the American Chemical society, 2009,238, 487 COLL.
34. Carboni,D., Flavin, K., Servant, A., Gouverneur, V., Resmini, M. “First Example of molecularly imprinted nanogels with Aldolase type I activity” Chem. Eur. J. 2008, 23(14), 7059-7065.
33. Gul G., Hussain, S., Thomas MP, Resmini M., Verma CS, Thomas EW, Brocklehurst
K. “Generation of nuclephilic character in the Cys25/His159 ion-pair of papain involves Trp177 but not Asp 158”, Biochemistry,2008, 47, 2025-2035
32. Boucher G, Said B. Ostler, E., Resmini, M., Brocklehurst, K. and Gallacher, G .. “Evidence that the mechanism of antibody catalysed hydrolysis of arylcarbamates can be determined by the structure of the immunogen used to elicit the catalytic antibody”, 2007, Biochem. J. 401, 721-726.
31. 31. Pasetto P, Maddock SC , Resmini M. “Synthesis and characterization of molecularly imprinted catalytic microgels for carbonate hydrolysis”, Anal. Chim. Acta, 2005, 542, 66-75.
30. Chiva-Rodriguez, A., Hawkes, G.E., Berti, F., Benedetti, F., Resmini, M. “Stereoselective synthesis of a novel pseudopeptide hapten for the generation of catalytic antibodies” Tet. Asym. 2004, 15, 1847-1855.
29. Sonkaria S., Boucher, GJ.R., Florez-Alvarez, J., Said, B., Hussain S., OPstler, E.L., Gul, S., Thomas, E.W., Resmini, M., Gallacher G., Brocklehurst K ., “Evidence for ‘lock and key’ character in antiphosphonate hydrolytic antibody catalytic sites augmented by non-reaction centre recognition: variation in substrate selectivity between antiphosphonate antibodies, antiphosphate antibodies and hydrolytic enzymes” Biochem. J. 2004, 381, 125-130.
28. Maddock SC, Pasetto P, Resmini, M. “Novel imprinted soluble microgels with hydrolytic catalytic activity” Chem. Comm, 2004, 536-537.
27. Resmini M., Ostler, E.L., Gallacher, G., Brocklehurst, K., “Polyclonal catalytic antibodies”, review chapter in “Catalytic Antibodies: recent advances”, Ed, E. Keinan, Wiley Pub.,2004
26. Maggiotti V, Bahmanyar S, Reiter M, Resmini M, Houk KN, Gouverneur V “Unusual reversal of regioselectivity in antibody-mediated aldol additions with unsymmetrical methyl ketones” Tetrahedron , 2004, 60/3, 619-632.
25. Reid JD, Hussain S, Bailey TSF, S onkaria S,. Sreedharan SK, Thomas EW, Resmini M, B rocklehurst K, “Isomerization of the actinidin molecule prior to enzyme-substrate complex formation: kinetic accessibility of additional steps in enzyme catalysis provided by solvent perturbation” Biochem. J. 2004, 378, 699-703.
24. Gul, S., Sonkaria, S., Pinitglang, S., Florez-Alvarez J., Hussain S., Thomas, EW, Ostler, EL, Gallacher, G, Resmini M, Brocklehurst, K. “Improvement in hydrolytic antibody activity by change in haptenic structure from phosphate to phosphonate with retention of a common leaving group determinant: evidence for the 'flexibility' hypothesis” Biochem. J. 2003, 376 (3), 813-821.
23. Hussain S; Pinitglang S; Bailey TSF; Reid JD; Noble M; Resmini M; Thomas EW; Greaves RB; Verma CS; Brocklehurst K “Variation in the pH-dependent pre-steady-state and steady-state kinetic characeristics of cysteine-proteinase mechanism: evidence for electrostatic modulation of catalytic-site function by the neighbouring carboxylate anion” Biochem. J. 2003, 372, 735-746.
22. Ostler EL; Dean CJ, Barber N, Valeri M, James S, Resmini, M, Boucher G, Romanov C, Brocklehurst K, Gallacher G “A rat monoclonal antibody that catalyses the hydrolysis of a nitrophenyl-beta-lactam” Biochem Biophys Res Commun , 2002 299 (2), 273-276.
21. Ostler EL, Resmini M., Brocklehurst K, Gallacher G “Polyclonal catalytic antibodies”2002, J. Immunol Method , 269(1-2), 111-124.
20. Maggiotti V , Bahmanyar S, Houk KN, Gouverneur V, Resmini M.“Theoretical studies on the antibody-catalyzed aldol reaction involving unsymmetrical enamine intermediates.”2002 Abstr Pap Amer Chem Soc , 223, 100.
19. Maggiotti V, Resmini M, Gouverneur, V “Unprecedented regiocontrol using an aldolase I antibody” ( 2002 ) Abstr Pap Amer Chem Soc , 223, 268.
18. Maggiotti V, Resmini M, Gouverneur V “Unprecedented regiocontrol using an aldolase I antibody” 2002Angew Chem Int Ed . 41(6), 1012-1016.
17. Ostler EL, Resmini M, Boucher, G, Romanov N, Brocklehurst K, Gallacher G “Polyclonal antibody-catalysed hydrolysis of a beta-lactam”2002 Chem Comm , (2), 226-227.
16.

Florez-Alvarez J, Brocklehurst K, Gallacher G, Resmini M.“Synthesis of an aminoalcohol hapten for the generation of catalytic antibodies”, 2002, Tet Lett , 43(1), 171-174.

15. Brocklehurst K, Resmini M , Topham CM, “Kinetic and titration methods for determination of active site contents of enzyme and catalytic antibody preparations”, 2001, Methods , 24(2), 153-167.
14. Krell T, Maclean J, Boam DJ, Cooper A, Resmini M, Brocklehurst K, Kelly SM, Price NC, Lapthorn AJ, Coggins JR “Biochemical and X-ray crystallographic studies on shikimate kinase: The important structural role of the P-loop lysine”, 2001, Protein Sci , 10(6), 1137-1149.
13. Topham C. M., Gul S., Resmini M. , Sonkaria S., Gallacher G, Brocklehurst K “The kinetic basis of a general method for the investigation of active site content of enzymes and catalytic antibodies: first-order behaviour under single-turnover and cycling conditions” J. Theoret. Biol. 2000,204, 239-256.
12. Resmini M, Gul S, Carter S, Sonkaria S., Topham C.M., Gallacher G., Brocklehurst K “A general kinetic approach to investigation of active site availability in macromolecular catalysts” Biochem J. 2000, 346, 117-125.
11. Resmini M, Gul S, Sonkaria S., Gallacher G, Brocklehurst K “Determination of the catalytic site content of a polyclonal catalytic preparation”, Biochem. Soc. Trans., 26, 1998, S170.
10. Bastiani E., Benedetti F., Berti F., Flego M., Resmini M. “A competitive assay for the detection of esterolytic activity of antibodies and enzymes” Analyt. Biochem. , 256, 1998, 67-73.
9. Resmini M., Vigna R., Simms C., Barber N.J.,.Hagi-Pavli E.P,.Watts A.B, Verma C., Gallacher G, Brocklehurst K “Characterisation of the hydrolytic activity of a polyclonal catalytic antibody preparation by pH-dependence and chemical modification studies. Evidence for the involvement of Tyr and Arg sidechains as hydrogen bond donors”, Biochem. J. , 326, 1997, 279-287.
8. Carter S, Resmini M, Simms C., Sreedharan S.K., Gallacher G, Brocklehurst K “Are polyclonal catalytic antibodies heterogeneous?”, Biochem. Soc. Trans. , 25, 1997, 865.
7. Annunziata F., Ferrari M.,Papeo G, Resmini M, Sisti, M “Asymmetric synthesis of 4(R)tert-butyl-8a (S) hydroxycarbonyl-4,6,7,8,8a,9-hexahydro-1-alkyl-pyrrolo [ 3,2-f ] indolizines via intramolecular iminium ion cyclization”, Synt. Comm. , 27(1), 1997, 23-28.
6. Busch M.H.A., Boelens H.F.M.,.Kraak H. Poppe J.C,, Meekel A.P, Resmini M. “Critical evaluation of the applicability of capillary zone electrophoresis for the study of hapten-antibody complex formation”, J. Chromat. A., 744, 1996, 195-203.
5. Resmini M, Meekel A.P, Pandit U.K “Catalytic antibodies: regio- and enantioselectivity in a hetero Diels-Alder reaction”, J. Pure Appl. Chem. ,vol 68, 1996, 2025-2028.
4. Meekel A.P, Resmini M , .Pandit U.K “Regioselectivity and enantioselectivity in an antibody catalysed hetero Diels-Alder reaction”, Bioorg. Med. Chem. ,vol 4, n.7, 1996, 1051-1057.
3. Meekel A.P, Resmini M , Pandit U.K “First example of an antibody-catalysed hetero Diels-Alder reaction”, . Chem. Comm ., 5, 1995, 571-5722.
2. Ferrari M., Orsini F, Resmini M, Sisti, M “The unusual reactivity of 9-oxa-4-thia-tetracyclo [ 5.5.1.0 2,7 .0 10,13 ] tridecan-12-one-3-spiro-1'-cyclopentan-3'-ones : a molecular modelling study”, J. Mol. Struct. (Theochem ), 309, 1994, 105-112.
1. Jommi G., Orsini F., Resmini M, Sisti, M. “A stereoconvergent approach to cicyclopenta [ a.d ] cyclooctane terpenoids via a very mild Cope reaction”, 1991,Tet. Lett ., 32, , 696


PATENTS
bullet G. Jommi, M. Resmini, M. Sisti
Optically active derivatives of proline, their preparation and use as catalysts for diastereo-and enantioselective aldolic condensations
6/7/1993 MI A001459
bullet Gallacher G., Oestler E.L., Brocklehurst K., Romanov N., Resmini M.
Catalytic antibodies and their use in Prodrug activation
n. 0124473.0, 11/10/2001

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